Serious Mental Illnesses lack effective treatment
Despite major advances in pharmacotherapy, there are still significant unmet needs with no effective treatments for some SMI symptoms.
The FDA has embraced “software as a medical device” (SaMD) enabling a path for clinically validated evidence-based digital therapeutics for psychiatry.1
Consumer-based mobile technology has advanced to allow for promising digital treatments for mental illness.
We are committed to developing, creating, and providing evidence-based solutions to address these unmet needs.
83% of individuals diagnosed with a schizophrenia spectrum disorder (n=40) would use a computer game that was recommended by their doctor to treat schizophrenia3
83% of mental health clinicians surveyed (n=29) would prescribe a FDA-approved digital therapeutic to treat symptoms of schizophrenia3
82% of mental health clinicians surveyed (n=27) believe that an evidence-based digital therapeutic could treat symptoms of schizophrenia3
PIPELINE
NST-SPARK: Therapeutic Augmented Reality for Schizophrenia
Negative symptoms of schizophrenia obstruct reward circuitry in the brain.
North Shore’s proprietary augmented reality therapeutic activates reward circuitry, driving engagement and cementing durable therapeutic outcomes.
NST-SPARK - Phase 1B Study (completed September 2024)
Goal: Preliminary study to investigate the feasibility of NST-SPARK, an augmented reality (AR) application, as a cognitive therapy tool for managing negative symptoms of schizophrenia.
Result: 20 participants engaged in gamified activities aimed at reducing defeatist beliefs. High acceptance and engagement with the app were observed, with participants showing positive attitude shifts. 90% of participants demonstrated concrete progress towards a life goal. Results are promising, and a controlled trial to assess efficacy is the next step.
Study details: https://clinicaltrials.gov/study/NCT06653829
Preprint paper: https://www.medrxiv.org/content/10.1101/2024.10.28.24315453v1.full.pdf
TEAM
Featured
We are building a unique team of mental health experts, patient advocates and cutting edge technologists all united in the mission to improve the lives of people suffering with serious mental illness. To be considered for our Team, send a note to careers@northshore.health
OPERATING VALUES
The North Shore Therapeutics Values define the way we operate and reflect our shared priorities. We express them through our company culture and individual behavior.
These four Values permeate all aspects of our business and we use these enduring Values to assess the “fit” of potential business investments, partnerships, and other corporate strategies.4 If you are aligned with these Values and interested in learning more, contact us.
